Choline: essential for lipid metabolism

Products containing
this ingredient

Choline is an essential nutrient and a source of methyl groups needed for many steps in metabolism. The body needs choline to synthesise phosphatidylcholine and sphingomyelin, two major phospholipids vital for cell membranes. Therefore, all plant and animal cells need choline to preserve their structural integrity.

In addition, choline is needed to produce acetylcholine, an important neurotransmitter for memory, mood, muscle control, and other brain and nervous system functions. Choline also plays important roles in modulating gene expression, cell membrane signaling, lipid transport and metabolism, and early brain development.

Humans can produce choline endogenously in the liver, mostly as phosphatidylcholine, but the amount that the body naturally synthesises is not sufficient to meet human needs. As a result, humans must obtain some choline from the diet. Premenopausal women might need less choline from the diet than children or other adults because estrogen induces the gene that catalyses the biosynthesis of choline. When a diet is deficient in folate, a B-vitamin that is also a methyl donor, the need for dietary choline rises because choline becomes the primary methyl donor.
Choline is an essential nutrient that plays a crucial role in various bodily functions.

While it is naturally found in many foods, some individuals may consider choline supplementation for various reasons, potential benefits of choline supplementation include:

Liver Health: Choline plays a role in fat metabolism and liver function. Choline deficiency can lead to fatty liver disease. Supplementing with choline may help protect the liver and promote its proper function.

Brain Health: Choline is a precursor to acetylcholine, a neurotransmitter that is essential for memory, learning, and cognitive function. Adequate choline levels may support brain health and cognitive function.

Pregnancy: Choline is particularly important during pregnancy as it is crucial for fetal brain development. Some studies suggest that choline supplementation during pregnancy may reduce the risk of neural tube defects and support cognitive development in children.

Muscle Function: Choline is involved in muscle function and may aid in muscle performance and endurance. Athletes and individuals engaging in regular physical activity may benefit from choline supplementation.

Cardiovascular Health: Choline is involved in the metabolism of homocysteine, an amino acid that, when elevated, is associated with an increased risk of cardiovascular disease. Adequate choline intake may help regulate homocysteine levels and support heart health.

Mood and Stress: Some research suggests that choline may have a role in mood regulation and stress management. It is a precursor to certain compounds in the brain, like phosphatidylcholine, which may have a calming effect.

Choline Deficiency Prevention: Certain medical conditions or dietary restrictions can lead to choline deficiency. In such cases, supplementation may be necessary to maintain adequate choline levels.

Neurological Disorders: Some research has explored the potential benefits of choline supplementation in neurological disorders like Alzheimer’s disease and other cognitive impairments. However, more research is needed in this area.

Choline is an essential nutrient that  can come from a variety of dietary sources, common dietary sources of choline include:

  1. Animal Products: Choline is abundant in animal-based foods. Eggs, specifically the egg yolk, are one of the richest sources of choline. Beef liver, chicken, and fish (such as salmon and cod) also contain significant amounts of choline.
  2. Dairy Products: Milk and dairy products like cheese and yogurt contain choline, although in smaller quantities compared to eggs and meat.
  3. Plant-Based Sources: While choline is less abundant in plant-based foods, some vegetables, legumes, and grains do contain it. Foods like broccoli, Brussels sprouts, peas, and quinoa contain moderate amounts of choline.
  4. Nuts and Seeds: Certain nuts and seeds, like almonds and sunflower seeds, contain choline, although the levels are not as high as in animal-based sources.
  5. Soy Products: Soybeans and soy-based products like tofu and soy milk can provide a good amount of choline.


Choline is important for brain health, liver function, and the synthesis of neurotransmitters and cell membranes. The recommended daily intake of choline can vary depending on factors like age, gender, and life stage, but it is typically in the range of 125-550 mg per day for adults. It’s important to include choline-rich foods in your diet to meet your nutritional needs, however supplemention can ensure an adequate intake of choline.

Products containing
this ingredient

related ingredients...

Unlock optimum energy, anti-ageing, health and wellness with our Swiss quality health products.

From nutrition tips to mindfulness practices, fitness routines to mental well-being strategies, we explore the pathways to a life filled with vitality. 

Explore the powerful components that play a pivotal role in supporting your overall well-being.

Unlock optimum energy, anti-ageing, health and wellness with our Swiss quality health products