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Zinc: a crucial essential mineral

Zinc is an essential mineral that plays a crucial role in many bodily function, provides valuable health benefits and plays a crucial role in various physiological processes, supplementation is beneficial for:

  1. Immune Support: known to support the immune system and help the body fight off infections playing a vital role in the development and functioning of immune cells.
  2. Wound Healing: essential for wound healing and tissue repair, helping in the production of collagen, a protein crucial for skin, and tissue health.
  3. Skin Health: effective in managing various skin conditions, such as acne, eczema, and psoriasis, helps to reduce inflammation and promote healthy skin.
  4. Antioxidant Properties: Zinc acts as an antioxidant, helping to protect cells from damage caused by free radicals, which are unstable molecules that can harm the body’s cells and DNA.
  5. Cognitive Function: Zinc is involved in cognitive functions and may support memory and learning. It plays a role in neurotransmitter regulation and brain health.
  6. Hormone Regulation: Zinc is necessary for the production and regulation of hormones, including insulin and sex hormones like testosterone and estrogen.
  7. Fertility and Reproductive Health: Adequate zinc levels are important for both male and female reproductive health. In men, it’s necessary for sperm production, while in women, it plays a role in the menstrual cycle.
  8. Growth and Development: Zinc is crucial for normal growth and development, especially in children. A deficiency can lead to growth retardation and delayed sexual maturation.
  9. Gastrointestinal Health: Zinc can help maintain the integrity of the gastrointestinal lining, potentially aiding in the treatment of conditions like diarrhea and inflammatory bowel disease (IBD).
  10. Eye Health: Zinc is found in high concentrations in the retina and may contribute to the health of the eyes. It is commonly included in eye health supplements.
Zinc for fatty acid metabolism and normal acid base metabolism

Zinc plays a role in various liver functions, including the metabolism of alcohol and detoxification processes. It is also involved in the synthesis of proteins and enzymes required for liver function. Maintaining an adequate but not excessive level of zinc is crucial for overall liver health.

It has been demonstrated that zinc deficiency is common in patients with liver cirrhosis, Zinc deficiency occurs in many types of liver disease, especially more advanced/decompensated disease.

Zinc supplementation has been best studied in experimental models of ALD where it blocks most mechanisms of liver injury, including increased gut permeability, endotoxemia, oxidative stress, excess TNF production, and hepatocyte apoptosis. Zinc may have some limited antiviral effect in HCV therapy. Importantly, zinc therapy has shown some promising antifibrotic effects in chronic HCV.

While zinc is important for overall health and zinc deficiency can lead to liver damage and dysfunction. This can result in conditions like non-alcoholic fatty liver disease (NAFLD) and liver cirrhosis, where the liver becomes scarred and less able to function properly.

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